Hello Zig Forums Today we are going to be talking about serotonin (5-HT for short).
So for the synthesis, you first will have your amino acids from your diet (tryptophan) then, the tryptophan will be converted via tryptophan hydroxylase. Would anyone like to say or guess the molecule's name that is made by this conversion?
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lsd-25?
Not quite user. Any other guesses before I give the answer?
niggerium-127
this isnt related to politics and will probably 404 but go on ...
At least you're trying. So biochemistry molecular names are very purposeful. A hydroxyl group (-OH) will be added to the 5 carbon of the tryptophan. Is that a good hint?
L-5OH-tryptophan is the next molecule. So next, we have an enzyme called L-amino acid decarboxylase. We want to get rid of the carbonyl functional group so we can get our 5-HT.
What happens to serotonin once it is made in the neuron?
Hydroxytryptophan
Another fun question. We have a drug that inhibits aromatic L-amino acid decarboxylase. What happens to the patient that takes this drug?