Bump for TATERTHOTS
America’s most widely consumed cooking oil causes genetic changes in the brain
Jason Davis
Blake Morris
huh
Jaxon Carter
Use only butter or lard, anything else other than animal fats and you’re destroying your arteries with machine lubricant.
Jose Martin
>TATERTHOTS
topkek
Logan Howard
>basedbean
basado
James Cox
I don't know boys, Canadian Canola oil is looking pretty fucking good right now, want me to broker your entry into the canola market for 3%?
Jonathan Foster
nigger. olive oil was good enough for the greeks and romans so it's good enough for me
Brody Green
That link doesn't lead anywhere, it just sends me to the home page of that magazine. For everyone's convenience:
Used for fast food frying, added to packaged foods, and fed to livestock, basedbean oil is by far the most widely produced and consumed edible oil in the U.S., according to the U.S. Department of Agriculture. In all likelihood, it is not healthy for humans.
It certainly is not good for mice. The new study, published this month in the journal Endocrinology, compared mice fed three different diets high in fat: basedbean oil, basedbean oil modified to be low in linoleic acid, and coconut oil.
The same UCR research team found in 2015 that basedbean oil induces obesity, diabetes, insulin resistance, and fatty liver in mice. Then in a 2017 study, the same group learned that if basedbean oil is engineered to be low in linoleic acid, it induces less obesity and insulin resistance.
However, in the study released this month, researchers did not find any difference between the modified and unmodified basedbean oil’s effects on the brain. Specifically, the scientists found pronounced effects of the oil on the hypothalamus, where a number of critical processes take place.
“The hypothalamus regulates body weight via your metabolism, maintains body temperature, is critical for reproduction and physical growth as well as your response to stress,” said Margarita Curras-Collazo, a UCR associate professor of neuroscience and lead author on the study.
The team determined a number of genes in mice fed basedbean oil were not functioning correctly. One such gene produces the “love” hormone, oxytocin. In basedbean oil-fed mice, levels of oxytocin in the hypothalamus went down.
Elijah Carter
olive/peanut oils are fine nigger
Liam Carter
The research team discovered roughly 100 other genes also affected by the basedbean oil diet. They believe this discovery could have ramifications not just for energy metabolism, but also for proper brain function and diseases such as autism or Parkinson’s disease. However, it is important to note there is no proof the oil causes these diseases.
Additionally, the team notes the findings only apply to basedbean oil — not to other onions products or to other vegetable oils.
“Do not throw out your tofu, basedmilk, edamame, or onions sauce,” said Frances Sladek, a UCR toxicologist and professor of cell biology. “Many onions products only contain small amounts of the oil, and large amounts of healthful compounds such as essential fatty acids and proteins.”
A caveat for readers concerned about their most recent meal is that this study was conducted on mice, and mouse studies do not always translate to the same results in humans.
Also, this study utilized male mice. Because oxytocin is so important for maternal health and promotes mother-child bonding, similar studies need to be performed using female mice.
One additional note on this study — the research team has not yet isolated which chemicals in the oil are responsible for the changes they found in the hypothalamus. But they have ruled out two candidates. It is not linoleic acid, since the modified oil also produced genetic disruptions; nor is it stigmasterol, a cholesterol-like chemical found naturally in basedbean oil.
Identifying the compounds responsible for the negative effects is an important area for the team’s future research.
“This could help design healthier dietary oils in the future,” said Poonamjot Deol, an assistant project scientist in Sladek’s laboratory and first author on the study.