A side effect of a drug that was originally used as an immunosuppressant could one day be used to treat baldness.
Researchers have found that the active compound stimulates human hair follicles to grow by targeting a protein that usually puts the breaks on. Publishing their results in the journal Plos Biology, they hope that it can now be developed into a form that could be used to treat alopecia.
“The fact this new agent, which had never even been considered in a hair loss context, promotes human hair growth is exciting because of its translational potential: it could one day make a real difference to people who suffer from hair loss,” said the University of Manchester’s Dr Nathan Hawkshaw, who co-authored the study, in statement.
The drug was actually originally designed to treat transplant patients, to suppress transplant rejection and autoimmune diseases. Known officially as Cyclosporine A (CsA), it has been commonly used since the 1980s, and does, unfortunately, have many side effects. One of the least serious – but most interesting – of these is the fact that it can sometimes cause unwanted hair growth.
The team first set about trying to figure out the molecular mechanism of the drug, before then carrying out a full gene expression analysis of individual human hair follicles, donated by people undergoing hair transplants, which had been treated with CsA. They were able to show that the drug inhibited a particular gene, SFRP1, which has in previous studies been shown to inhibit the growth of tissues, most crucially including hair follicles.
I represent a famous client who shall remain unnamed
Will this stuff hurt a fat guy in his 70's?
Dylan Powell
immunosuppressant Die from a cold,but have a body with a full head OF HAIR
Cooper Sanders
Chemotherapy just got a whole lot easier! Thanks science!
Wyatt Campbell
Nigger, even setting aside the immunological effects, cyclosporine analogs are godawful for your kidneys, heart, and digestive system. Don't take it without a damn good reason, such as "my immune system will destroy my organs if I don't".
I imagine they aren't going to just have people take it for baldness. The article clearly states.
Owen King
i looked up what caused the hair growth in articles, and apperantly it's corrolated to stimulation of the follicle stimulating hormone (FSH). FSH works by growing and maturating of germ cells of, among others, follicle cells. the problem with that, however, is that that kind of growth increases the chances of cancer quite high.
so basically, even in the best case scenario where they can make a compound that doesn't have immunosuppresive properties, they would have a hair grow serum that might cause cancer over prolonged use.
Jaxson Price
This. Other hair loss drugs, currently used, can wreck your endocrine system, leaving you more or less permanently chemically castrated. But at least you'll have hair when you kill yourself.
Aaron Rodriguez
Hey, people smoke voluntarily.
Hudson Perry
baldness is not that bad, for example, in the summer no insect will dare to land on your head
and with the correct sun positioning you can blind your enemies before striking them
Isaiah Bailey
Losing your hair is simply part of life if you're a man………….
Unless you're an effeminate little bitch with no testosterone…..
Losing your hair certainly doesn't prevent you from getting pussy.
Unless you're an effeminate little bitch with no testosterone, in which case you weren't getting any pussy to begin with, so the last thing you need to worry about is your hair…
Thomas Cooper
Doesn't everything
Cameron Long
...
Josiah Clark
I see nothing wrong with this.
Luke Adams
What does that mean? Is that supposed to be "puts the brakes on" or is "puts the breaks on" a figure of speech people use?
Testosterone is what causes baldness, so that fits.
Hunter Morris
I've never heard a woman in my entire life mention anything about 'not fucking a guy because he had male pattern baldness'….
I've never heard a woman say anything about not fucking a guy because he was bald, or going bald, or partially bald, or thinning at the top, or anything like that at all…
In fact, most women find bald men to be sexy…
Only sexless nerds who can't get any pussy dwell on this type of shit, because they've got too much time on their hands….
Guys who are going balls deep into pussy never waste their time thinking about stupid shit like this…
Alexander Davis
I'll tell you who fixates on hair loss, and how it will 'prevent them from getting girls' : GUYS WHO NEVER GET GIRLS IN THE FIRST PLACE
I'll tell you who fixates on penis size, always thinking about other guys penises, obsessing with 'how having a small penis will prevent them from getting girls' : GUYS WHO NEVER GET ANY PUSSY IN THE FIRST PLACE
I'll tell you what type of guy fixates on height, obsessively focusing on how 'being short will prevent them from getting girls' : GUYS WHO NEVER GET ANY PUSSY IN THE FIRST PLACE
There's a name for these people:
NERVOUS NELLIES
WORRY WORTS
CAPTAIN BRINGDOWN
If they would stop spending so much time worrying about needless bullshittin they can't control, and lighten up a little bit, they might actually start getting some pussy…
Nobody gives a fuck if you're going bald, or how tall you are, or how big your dick is… ONLY YOU WORRY ABOUT IT
And that type of worrying is exactly what makes you uncool, not fun to hang out with, the last guy a woman would want to date on this planet…
It shows a decided lack of self-confidence that is extremely unattractive
Alexander Lee
If only that were true. There are certainly women who are interested in hooking up with you, until you take your hat off and they see your hairline and the light in their eyes goes out, and they suddenly make excuses to be anywhere besides talking to you.
But it's not nearly as important as being tall, or buff, or rich. Or even having a good personality.
Asher Barnes
drug companies have no fucking shame,heart transplant donors will die because they cannot afford heart drugs because some men cannot face looking like phil collins.
Viagra was originally a heart drug for blood supply issues but it gave way to being a boner pill.
Antiretrovirals which stop you dying in five years of an agonizing death from AIDS along with kapposi sarcoma lesions like people did in the 80s are now used as a preventative measure against getting AIDS during bareback gay sex in PReP.
Gonorrhea and TB are now really resistant to antibiotics and we are being told to panic despite farmers using them willy nilly in massive amounts and there being no regulations on their use in massive parts of asia,africa and the americas.
we must worry because farangs in thailand are fucking bar girls raw and picking up this shit rawdogging them. there are literally pharmacies with no questions asked in the redlight district full of antibiotics, bargirls will work everyday because otherwise their pimps will beat them so of course they only take enough to feel better and pass on their resistant clap to you. and now we are all supposed to be surprised like chickens with open sores carrying campylobacter that can kill you.
Id rather shave my head or wear a doorag than have a organ transplant shit out on me with a full head of hair i got to impress laughingwhores.jpeg. fuck that im gonna be me and alive for as long as i can and not waste my money on looks or attractiion or boner enhancement to impress people. if someone doesn't like that they can suck my (unerect) cock when im 70.
