The most significant question for a Christian is "What does the Talmud say about Christ?" There are a number of passage which have been pointed to as potentially mentioning Christ, but this is a much debated topic.
One which is almost certainly a reference to Him, I think are the references to a certain Jesus who was the offspring of an adulterous union between Mary and a Roman soldier called Panthera. Given that this accusation is repeated by the pagan philosopher Celsus, I think this a reference to rumours about Jesus.
And, in denying the testimony of the Gospels, and impugning the BVM's character, it is to be rejected by any Christian.
So, I think there is clearly some objectionable material in the Talmud. Here, I would also add that it seems that some people draw too strong a conclusion from this: the Talmud is a 2,600 page long collection of a variety of differing kinds of literature from different periods and authors. To say that there is some "spirit of the Talmud" which somehow permeates every other statement in the Talmud, rendering it "Satanic" or worthless seems like a paranoid non-sequitur.
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The ethical content of the Talmud
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Often the ethical content is flat-out misrepresented. E.g. you'll often see denizens of far-right internet spaces post jpgs of "You Won't Believe These 10 Shocking Talmud Quotes!" with allegations that a particular passage of the Talmud permits for example, pedophilia or theft from Gentiles, but I really think the Jewish apologists show these claims to be pretty terrible.
On a traditionalist Catholic website, I found an allegedly "Sick and Insane Teaching of the Jewish Talmud" which is easily refuted just by looking up the passage in question. Real Jack-Chick level stuff.
E.g. "Abodah Zarah 17a. States that there is not a whore in the world that Rabbi Eleazar has not had sex with. "
So what? This occurs in a passage discussing a Jewish belief that being guilty of certain sins means be that an early physical death will be part of penance. It explicitly names Eleazar's behaviour as sinful not as some kind of demonstration that "Rabbis are allowed to do anything!" Here is the passage in full:
"And does not one die on renouncing sins other [than idolatry]? Surely it has been taught: It was said of R. Eleazar b. Dordaya that he did not leave out any harlot in the world without coming to her. Once, he heard that there was a certain prostitute in one of the towns by the sea who accepted a purse of coins for her hire. He took a purse of coins and crossed seven rivers for her sake. As he was with her, she blew forth breath and said: 'As this blown breath will not return to its place, so will Eleazar b. Dordaya never be received in repentance.' He thereupon went, sat between two hills and mountains and exclaimed: 'O, ye hills and mountains, plead for mercy for me!' They replied: 'How shall we pray for thee? We stand in need of it ourselves, for it is said, "For the mountains shall depart and the hills be removed!" So he exclaimed: 'Heaven and earth, plead for mercy for me!' They, too, replied: How shall we pray for thee? We stand in need of it ourselves, for it is said, "For the heavens shall vanish away like smoke, and the earth shall wax old like a garment." He then exclaimed: 'Sun and moon, plead for mercy for me!' But they also replied: 'How shall we pray for thee? We stand in need of it ourselves, for it is said, "Then the moon shall be confounded and the sun ashamed." He exclaimed: Ye stars and constellations plead ye for mercy for me!' Said they: 'How shall we pray for thee? We stand in need of it ourselves, for it is said, "And all the hosts of heaven shall moulder away." Said he: The matter then depends upon me alone! He placed his head between his knees, he wept aloud until his soul departed. Then a bat-kol was heard proclaiming: 'Rabbi Eleazar b. Dordaya is destined for the life of the world to come!'(2) Now, here was a case of a sin [other than idolatry] and yet he did die! - In that case, too, since he was so much addicted to immorality it is as [if he had been guilty of] idolatry. Rabbi [on hearing of it] wept and said: One may acquire eternal life after many years, another in one hour! Rabbi also said: Not only are penitents accepted, they are even called 'Rabbi'!"